Anh Hua

Research Advisor:

Joann Sweasy

Research Topic:

Exploring the role of DNA glycosylase NEIL2 variants in cancer pathogenesis and treatment

Selected Publications:

Hua, A. B., Justiniano, R., Perer, J., Park, S. L., Li, H., Cabello, C. M., & Wondrak, G. T. (2019). Repurposing the Electron Transfer Reactant Phenazine Methosulfate (PMS) for the Apoptotic Elimination of Malignant Melanoma Cells through Induction of Lethal Oxidative and Mitochondriotoxic Stress. Cancers, 11(5), 590.

Russ, A., Hua, A. B., Montfort, W. R., Rahman, B., Riaz, I. B., Khalid, M. U., ... & Anwer, F. (2018). Blocking “don't eat me” signal of CD47-SIRPα in hematological malignancies, an in-depth review. Blood reviews, 32(6), 480-489.

Jandova J, Hua AB, Fimbres J, Wondrak GT. Deuterium Oxide (D₂O) Induces Early Stress Response Gene Expression and Impairs Growth and Metastasis of Experimental Malignant Melanoma. Cancers. 2021; 13(4):605. 

Selected Presentations:

“Targeting the redox vulnerability of ^V600EBRAF-mutated malignant melanoma cells using the electron transfer reactant PMS (phenazine methosulfate) as a mitochondria-directed redox chemotherapeutic” - SID meeting in Scottsdale, AZ, in May 2016

“Expression Of A Somatic Variant In The H2TH Motif Of The DNA Glycosylase NEIL2 Induces Cellular Transformation Via Loss Of Glycosylase And Decreased Lyase Activity” – Gordon Research Conference – Mammalian DNA Repair meeting in Ventura, CA, in November 2021