Isabelle Tobey

Research Advisor:

Samuel Campos

Koenraad Van Doorslaer

Research Topic:

Determining the impact of oncogenic human papillomaviruses (HPVs) on the DNA-sensing, cGAS/STING, pathway.

Selected Publications:

King K.M., Rajadhyaksha E.V., Tobey I.G., Van Doorslaer K. Synonymous nucleotide changes drive papillomavirus evolution. Tumor Virus Research. 2022, DOI:10.1016/j.tvr.2022.200248

Krolak T., Chan K. Y., Kaplan L., Huang Q., Wu J., Zheng Q., Kozareva V., Beddow T., Tobey I. G., … Chenghua G., Deverman B. E. A High-Efficiency AAV for Endothelial Cell Transduction Throughout the Central Nervous System. Nat Cardiovasc Res. 2022, DOI:10.1038/s44161-022-00046-4

Huang Q., Chan K. Y., Tobey I. G., Chan Y. A., Poterba T., Boutros C. L., … Deverman B. E. (2019). Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids. PLoS One. 2019, DOI:10.1371/journal.pone.0225206. 

Selected Awards/Honors:

National Cancer Institute T32 Integrative Cancer Scholars Training Grant

Selected Presentations:

Tobey I, Uhlorn B, Jackson R, King K, Campos S, Van Doorslaer K (2022, July) HPV Inhibition of cGAS/STING. DNA Tumor Virus Meeting, Cambridge, UK (Oral presentation)  

Tobey I, Uhlorn B, Jackson R, King K, Van Doorslaer K, Campos S (2021, November) Interplay of HPV and the cGAS/STING pathway. 34^th International Papillomavirus Conference, Virtual