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Danielle DiFranco

PhD Student
Headshot of student, Danielle DiFranco.
difranco@arizona.edu
Pronouns:
she, her, hers

Documents

Danielle-DiFranco_CV.pdf

Research Advisor:

Joyce Schroeder

Research Topics:

The role of nuclear epidermal growth factor receptor (EGFR) in cell migration for the promotion of wound healing and cancer metastasis

Selected Publications: 

Schuster KH, Zalon AJ, DiFranco DM, Putka AF, Stec NR, Jarrah S, Naeem A, Haque Z, Guan Y, McLoughlin HS. (2024). ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice. Molecular Therapy, 32(5), 1359-1372, DOI:
https://doi.org/10.1016/j.ymthe.2024.02.033

Schuster KH, DiFranco DM, Putka AF, Mato JP, Jarrah SI, Stec NR, Sundararajan VO, McLoughlin HS. (2023). Disease- associated oligodendrocyte signatures are spatiotemporally dysregulated in spinocerebellar ataxia type 3. Frontiers in Neuroscience, 17, 1118429, DOI: https://doi.org/10.3389/fnins.2023.1118429

Schuster KH, Zalon, AJ, Zhang H, DiFranco DM, Stec N, Blumenstein K, Pierce A, Guan YF, Paulson HL, McLoughlin HS. (2022). Impaired oligodendrocyte maturation is an early feature in SCA3 disease pathogenesis. Journal of Neuroscience, 42(8), 1604-1617, DOI: https://doi.org/10.1523/JNEUROSCI.1954-20.2021.

Selected Presentations: 

DiFranco DM, Schroeder J: Oxidative Stress Drives Nuclear Localization of EGFR in Epithelial Cells to Promote Cell Migration. Poster. The 39th Annual Symposium of The Protein Society. June 2025.

DiFranco D, Schroeder J: A wound that never heals: Drivers of nuclear EGFR. Poster. The University of Arizona Cancer Center Annual Scientific Retreat. November 2024.

DiFranco DM, Hecksel R, Schroeder J: The role of nuclear epidermal growth factor receptor in cell migration and wound healing. Poster. Ginny L. Clements Breast Cancer Research Institute Annual Symposium. April 2024.

DiFranco DM, Schroeder J: The role of nuclear epidermal growth factor receptor in cell migration and wound healing. Poster. AACR Special Conference – Advances in Breast Cancer Research. October 2023.

Degrees

  • University of Michigan, BS, Molecular, Cellular, and Developmental Biology, 2022

Awards

  • Andrew C. Comrie Graduate Interdisciplinary Programs Doctoral Fellowship, 2025-2026
  • Herbert E. Carter Travel Award, 2025 Herbert E. Carter Travel Award, 2023